Difference between revisions of "2009 Summer Project Week Multimodal SPL Brain Atlas"

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==Key Investigators==
 
==Key Investigators==
* BWH: Ion-Florin Talos
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* BWH: Ion-Florin Talos, Michael Halle, Wendy Plesniak
* Utah:
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* GE: Jim Miller
* UNC:
 
* Georgia Tech:
 
  
 
<div style="margin: 20px;">
 
<div style="margin: 20px;">
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<h3>Objective</h3>
 
<h3>Objective</h3>
To create a segmentation pipeline for thalamic nuclei
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To explore ways of linking the image data of the SPL multi-modal brain atlas (label maps, 3D-models) with ontological information on brain morphology and function
  
  
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<h3>Approach, Plan</h3>
 
<h3>Approach, Plan</h3>
apply the spectral clustering approach to delineating the major thalamic nuclei in a high-resolution, volumetric DTI-dataset (voxel size 1 mm, 120 gradients)
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* continue work on XML-based intermediate data representation that supports anatomical hierarchies and can describe arbitrary overlapping image regions (e.g. brain functional systems)
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* application integration of the new XML-based data representation (3D-Slicer)
  
 
==References==
 
==References==
*Zyian U, Tuch D, Westin CF, Segmentation of Thalamic Nuclei from DTI Using Spectral Clustering, Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist Interv. 2006;9(Pt 2):807-14.
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1. Talos IF, Rubin DL, Halle M, Musen MA, Kikinis R. A prototype symbolic model of canonical functional neuroanatomy of the motor system. J Biomed Inform. 2008 Apr;41(2):251-263. PMID: 18164666. PMCID: PMC2376098.
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2. Rubin DL, Talos IF, Halle M, Musen MA, Kikinis R. Computational neuroanatomy: ontology-based representation of neural components and connectivity. BMC Bioinformatics 2009; 10(Suppl 2):S3. PMID: 19208191. PMCID: PMC2646240.

Revision as of 15:30, 19 June 2009

Home < 2009 Summer Project Week Multimodal SPL Brain Atlas

Key Investigators

  • BWH: Ion-Florin Talos, Michael Halle, Wendy Plesniak
  • GE: Jim Miller

Objective

To explore ways of linking the image data of the SPL multi-modal brain atlas (label maps, 3D-models) with ontological information on brain morphology and function


Approach, Plan

  • continue work on XML-based intermediate data representation that supports anatomical hierarchies and can describe arbitrary overlapping image regions (e.g. brain functional systems)
  • application integration of the new XML-based data representation (3D-Slicer)

References

1. Talos IF, Rubin DL, Halle M, Musen MA, Kikinis R. A prototype symbolic model of canonical functional neuroanatomy of the motor system. J Biomed Inform. 2008 Apr;41(2):251-263. PMID: 18164666. PMCID: PMC2376098. 2. Rubin DL, Talos IF, Halle M, Musen MA, Kikinis R. Computational neuroanatomy: ontology-based representation of neural components and connectivity. BMC Bioinformatics 2009; 10(Suppl 2):S3. PMID: 19208191. PMCID: PMC2646240.