Difference between revisions of "2010 Summer Project Week Cortical Thickness Analysis"

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Image:PW-MIT2010.png|[[2010_Summer_Project_Week#Projects|Projects List]]
 
Image:PW-MIT2010.png|[[2010_Summer_Project_Week#Projects|Projects List]]
 
Image:Arctic_Logo.png‎|[http://www.nitrc.org/projects/arctic ARCTIC: Automatic Regional Cortical ThICkness]
 
Image:Arctic_Logo.png‎|[http://www.nitrc.org/projects/arctic ARCTIC: Automatic Regional Cortical ThICkness]
Image:BrainDevelopment.jpg|Brain development
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Image:BrainDevelopment.jpg|[http://www.nitrc.org/projects/gambit GAMBIT: Group-wise Automatic Mesh-Based analysis of cortIcal Thickness ]
 
Image:MeshBasedCortThick_CorticalThickness.jpg|Cortical thickness on white matter surface
 
Image:MeshBasedCortThick_CorticalThickness.jpg|Cortical thickness on white matter surface
 
Image:MeshBasedCortThick_SulcalDepth.jpg‎|Sucal depth on genus-zero cortical surface
 
Image:MeshBasedCortThick_SulcalDepth.jpg‎|Sucal depth on genus-zero cortical surface

Revision as of 21:43, 15 June 2010

Home < 2010 Summer Project Week Cortical Thickness Analysis


Key Investigators

  • UNC: Clement Vachet, Heather Cody Hazlett, Martin Styner

Objective

We would like to create end-to-end applications within Slicer3 allowing individual and group analysis of regional (voxel-based) and local (mesh-based) cortical thickness.

Such a workflow applied to the young brain (2-4 years old) is our goal in order to start a longitudinal study of early brain development in autism (UNC DBP).

See our Roadmap for more details.




Approach, Plan

Our approach is described in the following wiki pages:

Our plan for the project week is to:

  • Follow-up on ARCTIC: Make it directly available as a 3D Slicer extension on MAC (compilation issues apparently)
  • Follow-up on GAMBIT: continue its developmenent, e.g by prodiving new 3D Slicer MRML scenes for quality control

Progress


Delivery Mechanism

This work will be delivered to the NA-MIC Kit as a:

  1. ITK Module
  2. Slicer Module
    1. Built-in
    2. Extension -- commandline - YES
    3. Extension -- loadable
  3. Other (Please specify)

References

  • I. Oguz, M. Niethammer, J. Cates, R. Whitaker, T. Fletcher, C. Vachet, and M. Styner, Cortical Correspondence with Probabilistic Fiber Connectivity, Information Processing in Medical Imaging, IPMI 2009, LNCS, in print.
  • H.C. Hazlett, C. Vachet, C. Mathieu, M. Styner, J. Piven, Use of the Slicer3 Toolkit to Produce Regional Cortical Thickness Measurement of Pediatric MRI Data, presented at the 8th Annual International Meeting for Autism Research (IMFAR) Chicago, IL 2009.
  • C. Vachet, H.C. Hazlett, M. Niethammer, I. Oguz, J.Cates, R. Whitaker, J. Piven, M. Styner, Mesh-based Local Cortical Thickness Framework, UNC Radiology Research Day 2010 abstract
  • C. Mathieu, C. Vachet, H.C. Hazlett, G. Geric, J. Piven, and M. Styner, ARCTIC – Automatic Regional Cortical ThICkness Tool, UNC Radiology Research Day 2009 abstract