Difference between revisions of "2010 Summer Project Week MRSI module and SIVIC interface"
(Created page with '__NOTOC__ <gallery> Image:PW-MIT2010.png|Projects List Image:Spectral fitting mrs.png|Fitting metabolite models to the MRS signal of tumorou…')
Revision as of 18:42, 31 May 2010Home < 2010 Summer Project Week MRSI module and SIVIC interface
- MIT: Bjoern Menze, M Phothilimthana, Polina Golland
- UCSF: Olson Beck, Jason Crane (Nelson Lab)
Magnetic resonance spectroscopic imaging (MRSI) is a non-invasive diagnostic method used to determine the relative abundance of specific metabolites at arbitrary locations in vivo. Certain diseases -- such as tumors in brain, breast and prostate -- can be can be associated with characteristic changes in the metabolic level.
The objective of the current project is to develop a module proving the means for the processing and visualization of MRSI -- and thus for a joint analysis of magnetic resonance spectroscopic images together with other imaging modalities -- in Slicer.
Spectral fitting routines have been implemented, using a HSVD filter for water peak removal and baseline estimation, and a constrained non-linear least squares optimization for the fit of the resonance line models. Current fitting routines require, however, several external software libraries not to be distributed, installed and used easily.