2011 Summer Project Week Segmentation TBI

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Full Title of Project

Key Investigators

  • Utah: Bo Wang, Marcel Prastawa, Guido Gerig
  • UCLA: Jack Van Horn, Andrei Irimia, Micah Chambers


Objective

Traumatic brain injury (TBI) occurs when an external force traumatically injures the brain. TBI is a major cause of death and disability worldwide, especially in children and young adults. TBI affects 1.4 million Americans annually. The UCLA medical school has been working on this topic for years.

On anatomical MRI scans, to quantitatively analyze the cortical thickness, white matter changes, we need to have a good segmentation on TBI images. However, for TBI data, standard automated image analysis methods are not robust with respect to the TBI-related changes in image contrast, changes in brain shape, cranial fractures, white matter fiber alterations, and other signatures of head injury.

We're working on the segmentation of Longitudinal TBI data.

Approach, Plan

Our plan for the project week:

  • Test our preliminary code
  • Discuss with collaborators and try to refine the algorithm

Progress