Difference between revisions of "CTSC:TTIC.033010"

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(Created page with '1. Consultation: new request: My dissertation is researching the back of the normal eye. Would you recommend where I could use a microscope that has X-Y automatic platform so tha…')
 
 
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1. Consultation: new request:
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Back to [[Collaboration:Harvard_CTSC|Collaboration:Harvard_CTSC]]
My dissertation is researching the back of the normal eye. Would you recommend where I could use a microscope that has X-Y automatic platform so that I could use tiling to make a composite picture of the entire retina or eye-cup flatmount? The blood vessels are stained fluorescent green (FITC), the cells are fluorescent red (Alexa 568) and the nuclei infared (TOPRO-3).  So far I have been able to image them with an old Leica Confocal using a Z-stack of 25 - 30 um thickness for a flatmount of just the retinal, 50 um for the whole eye-cup with optic nerve attached. 25X immersion objective had high resolution and a long working distance that allowed visualization of the blood vessels wrapped around the optic nerve. 40X - 63X distinguish nuclei of these irregularly shaped cells from high background around the optic disc.
+
<br>
 
My preliminary test run with deconvolution in OpenLab on images made on our regular fluorescent microscope, a Leica DM-RXA, may mean that it is not be necessary that the microscope be confocal, as long as it has an automated Z control. On another note, would 3-D Slicer be useful for reconstructing an image of the back of the eye from a combination of confocal microscope z-stack images and OCT (sonic-based imaging)?
 
  
2. Education program:
+
'''Agenda'''
a. update on 2nd cardiovascular session and 1st oncology session
+
 
b. policy for file sharing
+
# Consultations: update on on-going consultations
c. New material for hands-on workshops
+
# Education program
3. RSNA education proposal and reading room of the future
+
# Year 3 budget
4. Multi-center trial
+
#  RSNA education proposal and reading room of the future
 +
# Multi-center trial<br>
 +
 
 +
 
 +
== Harvard Translational Imaging Consortium Meeting Minutes March 30, 2010 ==
 +
 
 +
In attendance:
 +
 
 +
* Valerie Humblet
 +
* Randy Gollub
 +
* Wendy Plesniak
 +
* Gordon Harris
 +
* Charles Guttmann
 +
* Clare Tempany
 +
* Gordon Williams
 +
* Neil Rofsky
 +
* Jeff Yap
 +
* Ron Kikinis
 +
* Bill Hanlon
 +
* Stephan Voss
 +
* Simon Warfield
 +
 
 +
<br>
 +
 
 +
'''1. Consultations''' <br>
 +
 
 +
* We received a new consultation from someone who attend our educational sessions. Valerie and Ron will take care of it.
 +
 
 +
<br>
 +
 
 +
'''2. Education program''' <br>
 +
 
 +
* The attendance for the 1st oncology session was very low. However, the people in the audience were very motivated, it was the audience we target. Gordon W told the group that CCI found that half-day programs have the greatest fall out from registration to attendance.
 +
* Before the next offering, Valerie will send a reminder to the people who registered for the course.
 +
* Other way to advertise our courses:
 +
** people need to get the notice about the courses earlier, at least a couple of weeks in advance.
 +
** Jeff will contact the DFHCC clinical trial office and also announce the following oncology session on the DFHCC calendar.
 +
* For the next offering in the fall:
 +
** We have to decide if we want to do 1-hour sessions over lunchtime, we can also offer whole-day program.
 +
** At MGH try to get a room in the main campus, not the Simches building.
 +
** In Longwood, offer the sessions also at BIDMC and Childrens
 +
* New hands-on workshops offerings:
 +
** In May and June two additional Slicer workshops will be added (visualization and registration).
 +
** The new version of Slicer (tentative release in May 2010) will have a lot of interactive segmentation. Dominick Meier worked a lot on data fusion capabilities.
 +
** Stephan suggested to offer a workshop on Osirix with introduction, how to get access, how to do the basics, how to deindentifie data. Valerie and Wendy will look at the existing tutorials. Ron also mentioned that there are overlap between Osirix and Slicer.
 +
** Simon would be happy to develop a new tutorial with his softwares to be offered in the fall.
 +
 
 +
<br>
 +
 
 +
'''3. Year 3 budget''' <br>
 +
 
 +
* Every site has some extra budget under informatics and monitoring system, at some sites it needs to be re-budget, e.g: more allocation for travel to national meetings.
 +
 
 +
<br>
 +
 
 +
'''4. RSNA 2010''' <br>
 +
 
 +
* Valerie sent the proposal for 2 hands-on workshops and a refresher course. The documents are uploaded on the xythos website.
 +
* The proposals for the reading room of the future must be sent by April 1st. They will be sent separately and not as a Harvard Catalyst package. A folder will be created on the xythos website to upload them.
 +
 
 +
<br>
 +
 
 +
'''5. Multi-center trial''' <br>
 +
 
 +
* Bob had a vision to get a multi-institution trial. Being able to do a standardization within Harvard will show that multi-institutions can coordinate themselves.
 +
* A couple of first steps would be:
 +
** Get a proposal with an allocation of funds
 +
** To think about establishing an equivalent protocol
 +
** Evaluate the data analysis capabilities
 +
** Get a multi-institutional IRB
 +
* There are a couple of examples that we can use as model e.g. pediatric MS

Latest revision as of 19:18, 5 April 2010

Home < CTSC:TTIC.033010

Back to Collaboration:Harvard_CTSC

Agenda

  1. Consultations: update on on-going consultations
  2. Education program
  3. Year 3 budget
  4. RSNA education proposal and reading room of the future
  5. Multi-center trial


Harvard Translational Imaging Consortium Meeting Minutes March 30, 2010

In attendance:

  • Valerie Humblet
  • Randy Gollub
  • Wendy Plesniak
  • Gordon Harris
  • Charles Guttmann
  • Clare Tempany
  • Gordon Williams
  • Neil Rofsky
  • Jeff Yap
  • Ron Kikinis
  • Bill Hanlon
  • Stephan Voss
  • Simon Warfield


1. Consultations

  • We received a new consultation from someone who attend our educational sessions. Valerie and Ron will take care of it.


2. Education program

  • The attendance for the 1st oncology session was very low. However, the people in the audience were very motivated, it was the audience we target. Gordon W told the group that CCI found that half-day programs have the greatest fall out from registration to attendance.
  • Before the next offering, Valerie will send a reminder to the people who registered for the course.
  • Other way to advertise our courses:
    • people need to get the notice about the courses earlier, at least a couple of weeks in advance.
    • Jeff will contact the DFHCC clinical trial office and also announce the following oncology session on the DFHCC calendar.
  • For the next offering in the fall:
    • We have to decide if we want to do 1-hour sessions over lunchtime, we can also offer whole-day program.
    • At MGH try to get a room in the main campus, not the Simches building.
    • In Longwood, offer the sessions also at BIDMC and Childrens
  • New hands-on workshops offerings:
    • In May and June two additional Slicer workshops will be added (visualization and registration).
    • The new version of Slicer (tentative release in May 2010) will have a lot of interactive segmentation. Dominick Meier worked a lot on data fusion capabilities.
    • Stephan suggested to offer a workshop on Osirix with introduction, how to get access, how to do the basics, how to deindentifie data. Valerie and Wendy will look at the existing tutorials. Ron also mentioned that there are overlap between Osirix and Slicer.
    • Simon would be happy to develop a new tutorial with his softwares to be offered in the fall.


3. Year 3 budget

  • Every site has some extra budget under informatics and monitoring system, at some sites it needs to be re-budget, e.g: more allocation for travel to national meetings.


4. RSNA 2010

  • Valerie sent the proposal for 2 hands-on workshops and a refresher course. The documents are uploaded on the xythos website.
  • The proposals for the reading room of the future must be sent by April 1st. They will be sent separately and not as a Harvard Catalyst package. A folder will be created on the xythos website to upload them.


5. Multi-center trial

  • Bob had a vision to get a multi-institution trial. Being able to do a standardization within Harvard will show that multi-institutions can coordinate themselves.
  • A couple of first steps would be:
    • Get a proposal with an allocation of funds
    • To think about establishing an equivalent protocol
    • Evaluate the data analysis capabilities
    • Get a multi-institutional IRB
  • There are a couple of examples that we can use as model e.g. pediatric MS