Difference between revisions of "CTSC:multicenter101410"

From NAMIC Wiki
Jump to: navigation, search
Line 17: Line 17:
 
<br>
 
<br>
  
Modalities to start with: CT and MRI, protocol without contrast
+
===MRI neuroimaging virtual trial===
 +
 
 +
* It will be done with 3T MRI scanners, without contrast, with a multi-element head coil. Three sequences will be run: T2 weighted, FLAIR and MP RAGE. We will Implement common protocol with human phantoms.
 +
 
 +
 
 
Bodypart: neuroimaging, there is already a common neuro protocol for pediatric MS.
 
Bodypart: neuroimaging, there is already a common neuro protocol for pediatric MS.
Example: 3 sites, 3 MRI scanners 3T: 1 GE, 1 Philips and 1 Siemens:
+
 
Implement common protocol with human phantoms
+
 
 
take the dataset and look for reproducibility for 3 outcome measures; total brain volume, CFS and white/gray matter.  
 
take the dataset and look for reproducibility for 3 outcome measures; total brain volume, CFS and white/gray matter.  
 
understand where protocols are equivalent and different. Need to understand intra- and inter- variability
 
understand where protocols are equivalent and different. Need to understand intra- and inter- variability
 
Test difference obtained with different version of same software
 
Test difference obtained with different version of same software
 +
 +
=== Extension to other disease and modalities===
 +
 +
* We offer recommendation on the best phantoms for a specific disease. We also offer advices on calibration of theses phantoms.

Revision as of 19:27, 16 November 2010

Home < CTSC:multicenter101410

Back to Collaboration:Harvard_CTSC

Agenda

  1. establishment of the first virtual trial

Multicenter Clinical Trail Working group Meeting Minutes October 14, 2010

In attendance:

  • Valerie Humblet
  • Bob Lenkinski
  • Clare Tempany
  • Charles Guttmann
  • Simon Warfield


MRI neuroimaging virtual trial

  • It will be done with 3T MRI scanners, without contrast, with a multi-element head coil. Three sequences will be run: T2 weighted, FLAIR and MP RAGE. We will Implement common protocol with human phantoms.


Bodypart: neuroimaging, there is already a common neuro protocol for pediatric MS.


take the dataset and look for reproducibility for 3 outcome measures; total brain volume, CFS and white/gray matter. understand where protocols are equivalent and different. Need to understand intra- and inter- variability Test difference obtained with different version of same software

Extension to other disease and modalities

  • We offer recommendation on the best phantoms for a specific disease. We also offer advices on calibration of theses phantoms.