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  Back to [[NA-MIC_Collaborations|NA-MIC_Collaborations]]
 
  Back to [[NA-MIC_Collaborations|NA-MIC_Collaborations]]
  
'''Objective:''' To develop and disseminate learner oriented, tutorials and workshops that educate software developers and end-users about medical image analysis as they are being trained to use the NA-MIC toolkit.
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'''Objective:''' We are developing a software infrastructure within ITK for DTI analysis. This includes algorithms for statistical analysis of diffusion tensors, fiber tractography, image filtering and registration.
  
'''Progress:''' This year we delivered over 300 slides as part of 8 self-guided tutorials that include pre-processed, anonymized data sets on our Slicer 101 web page that had over 2000 hits in 200 days. More than 300 people attended the 11 workshops we offered this year at local NA-MIC sites, national conferences, and international meetings.
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'''Progress:'''
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* ''Geometric tools for diffusion tensor analysis.'' We have built a framework for geometric computations on tensors. This includes vector space operations on tensors as well as nonlinear operations that preserve the positive eigenvalues of the tensors. These geometric methods are the foundation for many of the tools below.
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* ''Statistical tools for diffusion tensor analysis.'' We have implemented methods for computing averages, covariances, and statistical group comparisons of diffusion tensor data.
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* ''Fiber tractography.'' We have developed software for tracking and viewing white matter fiber tracts. This tool has been combined with the statistical methods above for analysis and group comparisons of diffusion tensor data along white matter tracts.
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* ''Diffusion Tensor image filtering.'' We are building a framework within ITK for filtering diffusion tensor images. This includes several methods from the literature and both methods that filter estimated tensor fields and those that filter the original diffusion weighted data.
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* ''Diffusion Tensor image registration.'' We are building a framework within ITK for registration of diffusion tensor images. This requires image match metrics, interpolation of tensor images, and tensor image transformations.
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''Reference:'' Corouge, I., Fletcher, P.T., Joshi, S., Gilmore, J.H., Gerig, G. Fiber Tract-Oriented Statistics for Quantitative Diffusion Tensor MRI Analysis, presented at MICCAI 2005.
  
 
'''Key Investigators:'''
 
'''Key Investigators:'''
  
* Randy Gollub (MGH)
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* Utah: Tom Fletcher, Ross Whitaker
* Guido Gerig (UNC)
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* UNC: Isabelle Corouge, Casey Goodlett, Guido Gerig
* Martha Shenton, Sonia Pujol (BWH)
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* GE: Jim Miller
* Ross Whitaker (Utah)
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'''Links:'''
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* [[Progress_Report:Diffusion_Tensor_Statistics|Diffusion Tensor Statistics Progress Report]]
  
<br />'''Links:'''
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'''Representative Image and Descriptive Caption:'''
  
* [[Training:Events_Timeline|Training Events]]
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<div class="thumb tleft"><div style="width: 822px">[[Image:Tensor_interp.jpg|[[Image:Tensor_interp.jpg|Interpolation from a coronal slice of a DTI using the nonlinear averaging. Original data is on the left; the right image is created by up-sampling the image by two.]]]]<div class="thumbcaption"><div class="magnify" style="float: right">[[Image:Tensor_interp.jpg|[[Image:magnify-clip.png|Enlarge]]]]</div>Interpolation from a coronal slice of a DTI using the nonlinear averaging. Original data is on the left; the right image is created by up-sampling the image by two.</div></div></div>
* [[Slicer:Workshops:User_Training_101|Slicer 101 ]]
 

Revision as of 13:29, 18 December 2006

Home < NA
Back to NA-MIC_Collaborations

Objective: We are developing a software infrastructure within ITK for DTI analysis. This includes algorithms for statistical analysis of diffusion tensors, fiber tractography, image filtering and registration.

Progress:

  • Geometric tools for diffusion tensor analysis. We have built a framework for geometric computations on tensors. This includes vector space operations on tensors as well as nonlinear operations that preserve the positive eigenvalues of the tensors. These geometric methods are the foundation for many of the tools below.
  • Statistical tools for diffusion tensor analysis. We have implemented methods for computing averages, covariances, and statistical group comparisons of diffusion tensor data.
  • Fiber tractography. We have developed software for tracking and viewing white matter fiber tracts. This tool has been combined with the statistical methods above for analysis and group comparisons of diffusion tensor data along white matter tracts.
  • Diffusion Tensor image filtering. We are building a framework within ITK for filtering diffusion tensor images. This includes several methods from the literature and both methods that filter estimated tensor fields and those that filter the original diffusion weighted data.
  • Diffusion Tensor image registration. We are building a framework within ITK for registration of diffusion tensor images. This requires image match metrics, interpolation of tensor images, and tensor image transformations.

Reference: Corouge, I., Fletcher, P.T., Joshi, S., Gilmore, J.H., Gerig, G. Fiber Tract-Oriented Statistics for Quantitative Diffusion Tensor MRI Analysis, presented at MICCAI 2005.

Key Investigators:

  • Utah: Tom Fletcher, Ross Whitaker
  • UNC: Isabelle Corouge, Casey Goodlett, Guido Gerig
  • GE: Jim Miller

Links:

Representative Image and Descriptive Caption:

Enlarge
Interpolation from a coronal slice of a DTI using the nonlinear averaging. Original data is on the left; the right image is created by up-sampling the image by two.