Projects:FrontoTemporalConnectivityInSchizophreniaDuringSemanticMemory

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Objective: In this project, an event-related auditory semantic memory task is administered. Participants are presented with a semantic category and required to decide whether a subsequent word is a member of the category (e.g., vehicle-bus). To control for phonological processing, other items require a match-mismatch decision between pseudo-words constructed from reordered semantic items (e.g., yodb-rea).

Progress: To date, 6 patients with schizophrenia and 3 healthy controls have been studied with this task. Data will be available in year three.

Year Three Update: Data collection and analysis is ongoing. Updated results are expected at the end of year three.

Key Investigators:

  • Dartmouth: Andrew Saykin, Robert Roth, Laura Flashman, John West, Thomas McAllister
  • Harvard: Martha Shenton, Marek Kubicki

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