DTI Tractography Challenge MICCAI 2012

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The 2nd Edition of the MICCAI Grand Challenge on DTI Tractography will be held on Monday October 1st, 2012, as part of the 15th International conference on Medical Image Computing and Computer Assisted Intervention (MICCAI 2012) in Nice, France. The first Edition of the challenge was held at MICCAI 2011 in Toronto.


DTI tractography holds promises for mapping white matter pathways in-vivo. However, the validation of tractography results remains the major bottleneck to clinical usability and utility, since neurosurgeons and scientists face the challenge of selecting the appropriate tractography method in the absence of ground truth. This workshop aims at comparing tractography algorithms performances in the reconstruction of the corticospinal tract in a controlled environment using software generated DTI phantoms and in a clinical workflow of neurosurgical cases. Quantitative evaluation criteria will be based on fiber diffusion profiles, fiber geometry and distance between bundles. Clinical assessment will focus on anatomical correctness, depiction of lesion infiltration and tract displacement.


  • Sonia Pujol, Ph.D., Surgical Planning Laboratory, Brigham and Women’s Hospital, Harvard Medical School
  • Ron Kikinis, M.D., Surgical Planning Laboratory, Brigham and Women’s Hospital, Harvard Medical School
  • Martin Styner, Ph.D., Neuro Image Research and Analysis Laboratory, University of North Carolina
  • Alexandra Golby, M.D., Department of Neurosurgery, Brigham and Women’s Hospital, Harvard Medical School
  • Arya Nabavi, M.D., Department of Neurosurgery, University Hospital Schleswig-Holstein, Kiel, Germany
  • Guido Gerig, Ph.D.,The Scientific Computing and Imaging Institute, University of Utah
  • William Wells, Ph.D., Surgical Planning Laboratory, Brigham and Women’s Hospital, Harvard Medical School
  • Carl-Fredrik Westin, Ph.D., Laboratory of Mathematics in Imaging, Brigham and Women’s Hospital, Harvard Medical School
  • Sylvain Gouttard, M.Sc.,The Scientific Computing and Imaging Institute, University of Utah
  • Laurent Chauvin, M.Sc. Surgical Navigation and Robotics Laboratory, Brigham and Women’s Hospital, Harvard Medical School

Keynote Speaker

  • Carlo Pierpaoli, M.D.,Ph.D., National Institutes of Health

Important Dates

  • March 30: call for submission of papers to the workshop
  • June 30: workshop paper submission deadline
  • July 6: workshop paper acceptance
  • July 25: draft program of the workshop to be sent to MICCAI
  • July 30: deadline for camera ready papers
  • August 20: final version of the workshop proceedings to be sent to MICCAI.


  • 8:30-13:30 On-site challenge
  • 10:00-10:05: Opening remarks and Introduction
  • 10:05-10:20: DTI Tractography for Neurosurgical Planning: A Grand Challenge (Sonia Pujol, Ph.D.)
  • 10:20-10:30: Presentation of the Neurosurgical Cases (Alexandra Golby, M.D.)
  • 10:35-11:00: Coffee Break
  • 11:00-12:30: DTI Tractography Session
    • 11:00-11:10: Multi-fiber tractography for tumour resection with characterization of peri-tumoural tracts. Ali R. Khan, Maged Goubran, Jonathan C. Lau, Roy Eagleson, Terry M. Peters, and Sandrine de Ribaupierre. Robarts Research Institute, London, Canada
    • 11:10-11:20: Multifiber deterministic streamline tractography of the corticospinal tract based on a new diffusion model: Part II. Aymeric Stamm, Olivier Commowick, Patrick Perez, and Christian Barillot. INSERM U746-CNRS UMR6074-INRIA University of Rennes I, Rennes, France
    • 11:20-11:30: DTI Tractography Challenge 2012 - MITK Global tractography. Peter F. Neher, Bram Stieltjes, Marco Reisert, Hans-Peter Meinzer, and Klaus H. Fritzsche. German Cancer Research Center, Heidelberg, Germany
    • 11:30-11:40: DTI Tractography Challenge - MICCAI 2012: Global fiber-tractography based on Finsler distance. Antonio Tristan-Vega, Santiago Aja-Fernandez, and Carl-Fredrik Westin. University of Valladolid, Valladolid, Spain
    • 11:40-11:50: A novel iterative approach for segmentation and tractography of brain white matter fibers using MRI DTI data. Riza Alp Guler, Ali Demir, and Gozde Unal. Sabanci University, Istanbul, Turkey
    • 11:50-12:00: DTI-FT pipeline for cortico-spinal tract reconstruction at the Epilepsy Surgery Centre Niguarda Hospital. Alessio Moscato, and Francesco Cardinale, Niguarda Hospital, Milan, Italy
    • 12:00-12:10: Neurosurgical tracking at the Sherbrooke Connectivity Imaging Lab. Gabriel Girard, Maxime Chamberland, Jean-Christophe Houde, David Fortin, and Maxime Descoteaux. Sherbrooke University,Sherbrooke, Canada
    • 12:10-12:20: Derivation of fiber tracts representing the corticospinal tract using anatomical landmarks. Joy Matsui, Eun Young Kim, Vincent Magnotta, and Hans Jonhson. University of Iowa, Iowa City, USA
    • 12:20-12:30: Comparison of different reconstructions algorithms using CAMINO, FSL and MRTRIX packages to create cortico-spinal tracts in tumor patients.Sudhir K Pathak, Deepa Krishnaswamy, and Walter Schneider, University of Pittsburgh, Pittsburgh, USA
    • 12:30-12:40: Tractography in the CST using an Intrinsic Unscented Kalman filter. Hesamoddin Salehian, Guang Cheng, Jiaqui Sun, and Baba Vemuri. University of Florida, Gainesville, USA
  • 12:40-14:00: Lunch and posters
  • 14:00-14:45: Keynote Lecture "Considerations on the use of Diffusion MRI tractography to investigate brain connectivity" Carlo Pierpaoli, M.D., Ph.D., National Institutes of Health
  • 14:45-15:15: DTI Phantom (Martin Styner, Ph.D.)
  • 15:15-16:00: Coffee Break and Closed Review Session
  • 16:00-16:50: The Neurosurgeon’s Perspective on DTI Tractography (Alexandra Golby, M.D., and Arya Nabavi, M.D.)
  • 16:50-17:05: Neurosurgical Cases (Sonia Pujol, Ph.D.)
  • 17:05-18:00: Interdisciplinary Panel Discussion with all Teams, Jury Members and Neurosurgeons.

We expect an interactive and interdisciplinary discussion that will bring together 10 DTI tractography teams and five practicing neurosurgeons.

Event Website

To register to the challenge and access the datasets, please visit the MICCAI 2012 DTI Tractography Challenge website

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