Mbirn: MRI Calibration Milestones

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  • Core 1 Aims: Standardize and calibrate the acquisition of high-resolution structural MRI data to facilitate precise, quantitative, platform independent, multi-site evaluation of normal and pathological structural imaging data at multiple field strengths.
    • 1.1 Develop methods to improve structural T1- and FSE-based PD, T2-weighted, and FLAIR weighted MRI acquisition protocols that maximize image quality, improve sensitivity, reduce noise and enable quantitative analysis of healthy and diseased tissue across sites and instruments.
    • 1.2 Extend these methods to the acquisition of diffusion sensitive imaging, to improve diffusion MRI protocols and correction methods that minimize variability across sites while optimizing image quality and sensitivity for reconstructing fiber tracts and detecting abnormalities