2010 Summer Project Week Prostate MRI Segmentation

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  Projects List

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  T2w MRI, 1.5T pelvic coil

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  T2w MRI, 3.0T, endorectal coil

Key Investigators

• BWH: Andriy Fedorov
• GaTech: Yi Gao

Objective

Segmentation of the prostate gland is one of the steps in the planning of intra-operative guidance for image-guided biopsy and brachytherapy procedures. Accurate segmentation of the gland may be important for accurate calculation of the dose distribution in brachytherapy, and can be critical for accurate registration using surface-based approaches. We would like to automate the segmentation process, to reduce processing time, and improve its accuracy and reproducibility.

We will evaluate the applicability of the prostate segmentation tools developed by Georgia Tech (Yi Gao) on the 1.5T and 3.0T scans with and without endo-rectal coil.

Approach, Plan

This project is a follow-up on the previous developments in projects weeks of 2009-2010 (see references).

Our plan is to:

• make sure the software is compiled and applied correctly
• review processing pipeline
• evaluate the accuracy of segmentation compared with the manual outlines (we will use the publicly available dataset from MICCAI 2009 Prostate segmentation challenge (1.5T) as well as the images from on-going image-guided biopsy program at BWH (3T T2w, Siemens Magnetom)

Progress

Delivery Mechanism

This work will use the prostate segmentation tools earlier contributed to NAMIC Sandbox: http://viewvc.slicer.org/viewcvs.cgi/trunk/Queens/ProstateSeg

References

• Prostate segmentation at AHM SLC 2009
• Prostate registration at Boston 2009 meeting
• Prostate segmentation at AHM SLC 2010