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Back to NA-MIC Collaborations, Dartmouth DBP 1, Isomics Engineering

Neural Substrates Of Apathy

We recently observed reduced volume of the frontal lobe in patients with schizophrenia having high levels of apathy (link to journal below). In the present investigation we are extending our study of the structural correlates of apathy in schizophrenia using the NAMIC toolkit with an emphasis on basal ganglia.


Data acquired at 1.5T on 20 patients with schizophrenia and 20 healthy controls at Dartmouth. Have begun to apply 3D Slicer for manual segmentation. Additional subject accrual ongoing.

Key Investigators

  • Dartmouth DBP 1: Robert Roth, Laura Flashman, Andrew Saykin, Thomas McAllister
  • Isomics Engineering: Steve Pieper